Detalhe da pesquisa
1.
Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of phosphodiesterase 2 a.
Neurobiol Dis
; 191: 106393, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38154608
2.
Agonist-induced functional analysis and cell sorting associated with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain.
Genome Res
; 30(11): 1633-1642, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973039
3.
Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders.
Mol Psychiatry
; 26(9): 4570-4582, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33414502
4.
A novel microduplication in INPP5A segregates with schizophrenia spectrum disorder in the family of a patient with both childhood onset schizophrenia and autism spectrum disorder.
Am J Med Genet A
; 185(6): 1841-1847, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33720513
5.
Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome.
Cereb Cortex
; 29(8): 3241-3252, 2019 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30137253
6.
HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.
Nucleic Acids Res
; 46(12): 6344-6355, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29668986
7.
A new cis-acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization.
RNA
; 23(6): 899-909, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28258160
8.
Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons.
Proc Natl Acad Sci U S A
; 113(26): E3619-28, 2016 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233938
9.
Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis.
Stem Cells
; 35(2): 374-385, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27664080
10.
The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellum.
Nucleic Acids Res
; 43(17): 8540-50, 2015 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26250109
11.
Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA.
Nucleic Acids Res
; 43(3): 1834-47, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25628358
12.
A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability.
PLoS Genet
; 9(3): e1003367, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23555284
13.
Loss of FMR2 further emphasizes the link between deregulation of immediate early response genes FOS and JUN and intellectual disability.
Hum Mol Genet
; 22(15): 2984-91, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562910
14.
The 3' UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse.
Hum Mol Genet
; 22(10): 1971-82, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23390134
15.
Quantitative phosphoproteomics of murine Fmr1-KO cell lines provides new insights into FMRP-dependent signal transduction mechanisms.
J Proteome Res
; 13(10): 4388-97, 2014 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25168779
16.
A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model.
Genome Res
; 21(12): 2190-202, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21900387
17.
Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.
Hum Mol Genet
; 20(10): 1873-85, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21330300
18.
Fragile X Syndrome as an interneuronopathy: a lesson for future studies and treatments.
Front Neurosci
; 17: 1171895, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188005
19.
A novel function for fragile X mental retardation protein in translational activation.
PLoS Biol
; 7(1): e16, 2009 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19166269
20.
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.
Nature
; 442(7104): 814-7, 2006 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862120